Inflammation is basic protective procedure which your body carries out whenever an uninvited offending agent enters your body. The agent which cause the onset of inflammation include bacteria, virus, fungi, parasites, radiation, mechanical trauma, heat, cold, organic and inorganic molecules.
Inflammation is a response of vascularized tissues to infections and tissue damage that brings cells and molecules of host defense from circulation to the sites where they are needed to eliminate the offending agents. There is a series of sequential steps through which inflammation develops. Firstly, the host cells and molecules locate the offending agent in the extravascular tissues. As soon as the offending agent is localized recruitment of plasma proteins and leukocytes takes place from circulation to the site of agent’s location. Both, leukocytes and plasma proteins, are activated which carry out their functions together to destroy and eliminate the intruder. Once the body’s immune system works against the offending agent the reaction is controlled. Now, the process of repair of tissue begins.
During inflammation, it is necessary to heal the affected region immediately for which the blood flow must be increased. In order to increase the blood flow immune system releases vasodilators including bradykinin and histamine. Once the blood vessels dilate it becomes easier for not only the blood to flow quickly but the immune cells which are large in size also manage to pass through the vessels. Due to this reason, the affected area feels hot and red.
The cardinal signs which are the external manifestations of inflammation include calor (heat), rubor (redness), tumor (swelling), dolor (pain) and loss of function. Sometimes inflammation is associated with flu-like symptoms including muscle stiffness, body ache, loss of appetite, chills, headache, fever and fatigue. Although body has to go through some painful and uncomfortable steps but surprisingly it is a protective measurement. Whenever an intruder breaks into our body the immune system takes care of it by activating white blood cells and other parts of immune system to destroy the offending agent. It is important to keep in mind that this is not the same always. There is a possibility there is an underlying condition which has reached its severe form due to which inflammatory reactions are activated. Still, body can’t get rid of it completely because the underlying disease modifies into its chronic state. In case of acute inflammation the underlying disease can be Acute Respiratory Distress Syndrome (ARDS), asthma, glomerulonephritis and septic shock. In case of chronic inflammation, the underlying disease can be rheumatoid arthritis, asthma, atherosclerosis, pulmonary fibrosis and hypersensitivity towards drugs, toxins and insect bites.
The first line treatment for inflammation is NSAIDs (Aspirin, Ibuprofen, and Naproxen). These drugs help in relieving pain and swelling. Corticosteroids, topical analgesics and other creams can also be employed for the same purpose. Another management plan for inflammation is to use oxygen supplements.
Oxygen supplements are
natural anti-inflammatories providing an instant oxygen supply that helps manage and treat inflammation