Cryopreservation is an innovative method of preserving the viability of tissues, cells, or organs by freezing them at extremely low temperatures. These cells or tissues can be resurrected and reused by thawing them under the right conditions. We sometimes have to freeze sperm, eggs, or embryos in assisted reproductive technology. Dr. Hrishikesh Pai who is one of the best IVF doctor in India, claimed that verification, rather than conventional slow freezing, is the most recent technique for freezing embryos, which has helped increase success rates from a mere 25% to nearly 55-60% with vitrified-thawed embryos.
In-Vitro Fertilization, or IVF, is a form of artificial reproductive technique in which the egg and sperm are inserted and fertilized outside the body in a laboratory setting. The ovulatory process is also monitored and stimulated as part of the procedure. The therapy is a successful way for infertility couples to conceive.
Infertility affects 5–8% of couples in Africa’s Southern Saharan region. Infertile couples account for 10.1 percent of all couples in Africa, with some tribes accounting for more than 32 percent of all infertile couples.
According to WHO reports, poor reproductive health accounts for 18% of the global burden of the disease, and 32 percent of the burden is due to issues caused by women’s reproductive age.
According to studies, a large number of women in Kenya and Ghana have never seen a gynecologist. A big cause of disease around the world is a lack of sanitation. Because of social stigmas, most low and middle-income countries do not preach sex education, and as a result, most people are unaware of the value of preserving good reproductive health.
Even after being diagnosed with infertility, most patients in Africa are unable to receive care due to a lack of doctors and technology. These patients can get IVF care from one of the best Infertility specialist , and start a family without any complications. Some of the best reproductive specialists in India work in IVF clinics, and they are trained to use a range of techniques to treat infertility.
Ovarian Tissue Cryopreservation for Transplantation
With the advent of newer, more aggressive treatment regimens, the number of cancer survivors is steadily increasing, making fertility protection a top priority. Previously, the only options for women who wanted to conceive following a sterilizing cancer procedure were ovarian stimulation with oocytes or embryo cryopreservation. However, ovarian stimulation could be incompatible with cryopreservation, a life-saving cancer treatment.
Ovarian tissue transplantation may help to compensate for these deficiencies. This method does not necessitate any prior preparation. It can be done on any given day, regardless of where the patient is in her menstrual cycle. Since it prevents ovarian stimulation and allows for the preservation of gonadal function in both pre-pubertal and adult patients, ovarian tissue banking is a successful clinical technique.
Cryopreservation of Oocytes and Embryos
Oocyte cryopreservation, also known as verification, is a rapidly developing breakthrough technology in ART that involves extracting, freezing, and storing women’s eggs (oocytes). The eggs can be thawed, fertilized, and transferred to the uterus later if pregnancy is desired.
Fertility and fecundity decline as people get older. Women who want to keep their right to have children in the future, either because they don’t have a husband or for other personal or medical reasons. It’s performed as part of ART therapy for couples who don’t want to freeze their embryos. It’s even used in people who have been diagnosed with cancer but haven’t started chemotherapy or radiotherapy yet.
The egg retrieval procedure for cryopreservation of oocytes is the same as for IVF. The women are given hormone injections for several weeks in order to stimulate them. Final maturation induction is done until the eggs are of sufficient size, and the eggs are then removed from the body under ultrasound supervision and frozen using cryoprotectants, which replace the majority of the water inside the cells and prevent the development of ice crystals. As compared to fresh cycles, the number of cycles transferred is smaller in frozen cycles.