Weight Loss Drugs: 5 Weight Loss Pills Described with Pros & Cons

Weight loss comes in a simple formula—you eat less and move more. It’s a surefire technique, only that it is easier said than done. People struggle to achieve weight loss mainly because there are less motivational guides and more temptations around that might disrupt any success you achieve. It’s annoying to have to start over again a few more times after failing, that sometimes you become too tired to bother at all.

This is where weight loss pills comes in. They can help you get started with your regimen. We all need that extra lift to be able to enable change to takeover.

But of course, none of these diet pills are magic. In fact, the results from taking them are not nearly as impressive as surgery, but that is a different topic for another day. Diet pills are the cheaper alternative, and they need to form a triangular plan with healthful diet and exercise to be most effective for you.

The upside to this is that even the smallest of weight loss can have great benefits to anyone. Even when you lose only 5-10%, you will still see changes in blood sugar levels and blood pressure.


If you are in the obese category, which means a body mass index or BMI of 30, you are suggested to take weight loss pills to jumpstart your weight loss journey. If you are overweight (BMI of 27) you can also benefit from using these medications, granted that you have an existing medical conditon, such as cardiovascular problems or high blood pressure.

This is according to the Endocrine Society guidelines set to indicate that not everyone may use this type of pills. It’s a selective process. Weight loss pills are intended for people who are having a hard time starting their weight management training. Those who can benefit from weight loss drugs are people looking to supplement their dieting and exercising effort. These drugs help patients stick to a better lifestyle, thus encouraging the mentality of the patient.

Patients undergoing treatment using weight loss drugs are monitored strictly. If after three months they fail to shed at least 5% of their excess weight, they would be asked to discontinue using the current medication, because chances are they are not effective for him or her. Weight loss pills have different pattern of action for every individual, so there is a need to find the best one that suits you. It could be a journey of trial and error for some.

Like any medication, the weight loss pills also come with risks, and are up to medical practitioners to deem if the patient needs the treatment. If the benefits outweigh the risks, then a solid plan involving the use of a weight loss drug is engaged.


What drugs are available? If obesity is your biggest problem, then it will be a contest between the prescribed weight loss drugs approved by the Food and Drug Administration to help you shed that weight. Here are some details of each and how it can help treat long-term obesity.


Orlistat is readily available as an over-the-counter or a prescription weight loss pill. It is the most well-known around the world. Orlistat is branded as Alli for the OTC counterpart, and Xenical for the prescription.

Prescribing Orlistat to an overweight or obese patient entails instructing them to watch their diet. A low-fat low-calorie diet is the usual partner of this drug. It is a lipase inhibitor; this signifies that it blocks the action of lipase, a pancreatic enzyme that breaks down fat before it is taken in by the body.

Reported side effects of Orlistat include gassiness, bowel changes, and most commonly an oily bowel movement. Instead of the body breaking down fat and being taken up by the body, it is excreted through the stool unchanged. Some incidence of severe liver damage has also been noted, and thus the label was modified to have a warning in 2010.


Lorcaserin, with brand name Belviq, works by enhancing the feeling of being full as the drug acts on a specific serotonin receptor in the brain. This drug was approved by the FDA, following Orlistat in 2012.

When combined with a sound exercise and diet routine, Lorcaserin may have as much as 3-3.7% effectiveness on weight loss. Patients sans diabetes type 2 are found to have lost 5% of excess weight, which is the standard number for gauging a winning obesity treatment.

Some contraindications of Lorcaserin include using it with other selective serotonin reuptake inhibitors or SSRI’s because they have the same target which is serotonin.

Phentermine + topiramate

The combination of phentermine and topiramate was approved in 2012 and is sold by its brand name Qysmia. Both substances work to suppress hunger and facilitating the feeling of being full.

This combination drug has been shown to cause cleft palate in as early as the fetal stage, so women who are capable of child-bearing who need to take this drug are advised to take birth control pills in conjunction. There are also reports that indicate topiramate users can develop suicidal thoughts in prolonged use.

Phentermine + topiramate combination is, like any other weight loss drug, advisable to be taken with proper diet and exercise.

Bupropion + naltrexone

Another combination drug prescribed in weight loss is sold in its brand name Contrave. The packaging comes with a black warning from the FDA that means some serious side effects include having suicidal thoughts. As it affects the working of the brain by targeting the hypothalamus to inhibit hunger, patients taking this drug are prone to behavioral and mental changes.


Sletrokor is another emerging brand of weight loss pills that can be used effectively because of its natural ingredients. It acts to suppress hunger and at the same time enhances the metabolic function of the body, making it a double dose of weight loss action in one drug.

The best thing about Sletrokor is that it has no reported side effects aside from bowel changes. This may well be attributed to the fact that Sletrokor contains natural ingredients that are safely taken up by the body to promote weight loss.

Patients who use Sletrokor and taking care of their eating habits and physical activity may see better and faster results when using this drug.

When choosing the right weight loss drug for your obesity or overweight problem, make sure that you have reviewed the pros and cons of the drug you are about to take. Turn to the safest drug as much as possible, with the one known to be effective minus the side effects. Your health should always be top priority, so in addition to medical advice, weighing in the benefits and ensuring they surpass the risks should always be the first move in picking a weight loss drug.